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More than half (55 people) of people with a BMI below 25 report their main motivation for using a weight loss drug is to improve body confidence or self-esteem and around half (52 percent) of this cohort say that celebrity endorsement made them more open to trying the medication." "When prescribed by a registered doctor or a licensed prescribing pharmacist, with appropriate support in place, these medicines can be highly effective for some patients

GLP-1 and GIP receptor agonists seem to have a synergistic effect in weight reduction, although the mechanism is not yet clear [44]

These include Ozempic, which is FDA-approved for type 2 diabetes, and Wegovy, which is FDA-approved for chronic weight management

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